Tuesday, November 6, 2012

Glucose-Responsive Disassembly of Polymersomes of Sequence- Specific Boroxole-Containing Block Copolymers under Physiologically Relevant Conditions

Hyunkyu Kim, Young Ji Kang, Eun Sun Jeong, Sebyung Kang, and Kyoung Taek Kim


This group co-polymerized organicboronic acid functionalized styrene with functionalized maleimide groups through RAFT. This polymer self-assembled into polymersomes in water and was shown to bind sugars in water at neutral pH. At a high concentration of glucose (>0.3M), the polymersomes would dissassemble.

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