Supramolecular Nanostructures Formed by Anticancer Drug Assembly

JACS

http://pubs.acs.org/doi/abs/10.1021/ja3115983

 

 

 

The load of CPT on peptide via disulfylbutyrate linker and the assembly of these peptides to form nanoparticles for drug delivery. The kinetic release of CPT and in vitro dose-response relationship were studied.

Posted by Longyan Liao

Synthetic tool, amino acids

Control of Diastereoselectivity for Iridium-Catalyzed Allylation of a Prochiral Nucleophile with a Phosphate Counterion

Wenyong Chen and John F. Hartwig *

 

A useful way to synthesize enantio- and dia-stereomerically pure allyl-functionalized non-traditional aminoacids.

http://pubs.acs.org/doi/abs/10.1021/ja311363a 

Posted by Alex Zhukhovitskiy