Iron-Catalyzed Alkylations of Aryl Sulfamates and Carbamates

Org. Lett.
http://pubs.acs.org/doi/abs/10.1021/ol301681z

The alkylation of aryl sulfamates and carbamates using iron catalysis is reported. The method constructs sp²–sp³ carbon–carbon bonds and provides synthetically useful yields across a range of substrates . The directing group ability of sulfamates and carbamates, accompanied by their low reactivity toward conventional cross-couplings, renders these substrates useful for the synthesis of polyfunctionalized arenes.