N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex Catalyzed Suzuki-Miyaura Coupling of Aryl Sulfonates with Arylboronic Acids

N-Heterocyclic Carbene-Palladium(II)-1-Methylimidazole Complex Catalyzed Suzuki-Miyaura Coupling of Aryl Sulfonates with Arylboronic Acids

Zhan-Yong Wang, Gao-Qi Chen, and Li-Xiong Shao

http://pubs.acs.org/doi/abs/10.1021/jo301270t

In this paper, the authors show the first example of NHC-Pd(II) complex catalyzed Suzuki-Miyaura coupling of aryl sulfonates including tosylates, phenylsulfonates and even the less reactive mesylates with arylboronic acids.  The reaction behaves best if carried out in morpholine as solvent, and high temperatures (>100oC) are required.  Still, a useful reaction, and it uses the IPr NHC.