Chemoselective Cross-Coupling Reactions with Differentiation between Two Nucleophilic Sites on a Single Aromatic Substrate

Julian Linshoeft, Annika C. J. Heinrich, Stephan A. W. Segler, Paul J. Gates,† and Anne Staubitz* 
http://pubs.acs.org/doi/abs/10.1021/ol302571t

 

The stannyl-boronate above can be made easily from the corresponding bis-stannane by transmetallation with MeLi and quenching with a boronate reagent.  The reactions could be one-pot but have to be sequential.