Sunday, March 24, 2013

Clip chemistry

Oxidation-Accelerated Hydrolysis of the Ortho Ester-Containing
Acid-Labile Polymers
Cheng-Cheng Song, Ran Ji, Fu-Sheng Du, De-Hai Liang, and Zi-Chen Li

An interesting example of "clip" chemistry: cleavage of 4-(pinacolboryl)-benzyl ester using H2O2, resulting in a carboxylic acid and p-quinone methide (which eventually undergoes hydration).

No comments:

Post a Comment