Wednesday, December 5, 2012

Photoselective Delivery of Model Therapeutics from Hydrogels
Donald R. Griffin and Andrea M. Kasko

 Fluorescein, rhodamine, and aminomethylcoumarin acetate were linked to PEG macromers via several different photodegrable ortho-nitrobenzyl based linkers. The macromers were polymerized into gels through redox polymerization using APS (ammonia persulfate) and TEMED (N,N,N',N'-tetramethylenediamine). The rates of degradation and release of the linked molecules were observed at different wavelengths and found to differ for each molecule.

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