Thursday, February 7, 2013

Double Click: Dual Functionalized Polymeric Micelles with Antibodies and Peptides

Bethany Powell Gray, Shunzi Li, and Kathlynn C. Brown

http://pubs.acs.org/doi/full/10.1021/bc300498d

In this papers, the researchers used phage display to find peptides that bind specifically to biomarkers on cancer cells. Their results were tested with liposomes conjugated with these peptides on the surface either as a monomeric peptide or a tetrameric peptide, and tetrameric conjugation was shown to improve selective delivery.

Abstract Image

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