Thursday, February 7, 2013

Imaging Biodistribution of Nanomedicine through FRI and FMT

http://pubs.acs.org/doi/pdfplus/10.1021/nn303955n

Optical Imaging (OI) is becoming a very popular way to track changes in vivo. In this article, FRI (fluorescence reflectance imaging) is even predicted to surpass MRI in usage. FRI cannot be used for deep tissue imaging, but when paired with FMT (fluorescence molecular tomography) which uses lasers to excite near-IR fluorophores and uCT (microcomputed tomography) which helps to map the FMT signals, this becomes a powerful tool for noninvasively gaining quantitative biodistibution information.


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