An intrinsically fl uorescent cationic polyfl uorene ( CCP ) has been
designed, synthesized, characterized, and examined as a plasmid DNA
(pDNA) delivery vector.
CCP can effectively protect pDNA against nuclease degradation, which is
necessary for gene carriers. Green fluorescent protein (GFP) expression
experiments reveal that CCP can achieve efficient delivery and
transfection of pDNA encoding GFP gene with 92% efficiency, which is
higher than some of the commercial transfection agents.