Cancer Prognostics by Direct Detection of p53-Antibodies on Gold Surfaces by Impedance Measurements

Elisabet Prats-Alfonso,* Xavier Sisquella, Nadia Zine, Gemma Gabriel,
Anton Guimerà, F. Javier del Campo, Rosa Villa, Adam H. Eisenberg, Milan Mrksich, Abdelhamid Errachid, Jordi Aguiló, and Fernando Albericio*
 
http://onlinelibrary.wiley.com/doi/10.1002/smll.201102724/abstract

In this paper, impedance measurements of gold contacts functionalized with peptides that specifically bind to the p53 antibody are used to detect the antibody with high selectivity and at low concentrations (down to 10^-17 M).