Monday, July 2, 2012

DNA Block Copolymers: Functional Materials for Nanoscience and Biomedicine

Acc. Chem. Res.

In this Account, some examples of recent developments in the synthesis, structure manipulation and applications of DNA block copolymers (DBCs) are discussed. Achievements in synthesis of DBCs and their amplification based on molecular biology techniques are discribed. Future applications of DBCs are as follows. DBC micelles have served as drug-delivery vehicles, as scaffolds for chemical reactions, and as templates for the self-assembly of virus capsids. In nanoelectronics, DNA polymer hybrids can facilitate size selection and directed deposition of single-walled carbon nanotubes in field effect transistor (FET) devices.

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