Monday, July 30, 2012

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

High-Resolution Protein Structure Determination by Serial Femtosecond Crystallography

Sébastien Boutet et al.

http://www.sciencemag.org/content/337/6092/362.short

In this paper, the authors report a new technique called SFX to determine crystal structure of small crystals (on the order of 0.1-10 micrometers) that are susceptible to X-ray damage.  This technique relies on femtosecond pulses of x-rays, as well as on the introduction of sample as a liquid jet.

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