Pontus Lundberg,Bongjae F. Lee, Sebastiaan A. van den Berg, Eric D. Pressly, Annabelle Lee, Craig J. Hawker, and Nathaniel A. Lynd
This group synthesizes a degradable PEG-based polymer by making a
copolymer of ethylene oxide with epichlorohydrin followed by elimination
of the halide to incorporate degradable ethylene methylene oxide
copolymer with ethylene oxide. This polymer degrades as pH 5.0 at 37 C,
but is relatively stable over 70 hours at pH 7.4 at 6 C.